The modular high-efficiency filter (also known as “modular high-efficiency filter”) is a filtration device designed for large supply air ceilings and high-volume cleanroom scenarios. By integrating multiple independent HEPA/ULPA filter units (filter elements) within a unified framework, it ADAPTS to different size and air volume requirements. Based on the actual operation and maintenance scenarios of cleanrooms, its advantages and disadvantages are as follows, taking into account both technical features and practical feasibility: I. Core Advantages (Key Characteristics for Adapting to High-Demand Clean Environments) 1. Strong air volume adaptability, meeting the demands of large-scale scenarios The air volume of a single filter unit is typically 500-2000m³/h. By increasing or decreasing the number of units or customizing the frame size, the air volume can be flexibly configured from 1000-10000m³/h or more, perfectly matching large operating rooms, pharmaceutical filling workshops, semiconductor clean workshops and other supply air ceilings that require high air supply volume. Compared with a single large high-efficiency filter, the modular design can avoid the problem of uneven airflow caused by insufficient air volume of a single device, and is especially suitable for large-area supply air ceilings (such as laminar flow areas of ≥10 square meters). 2. The filtration efficiency is

To determine whether the supply air ceiling filter (with the core being HEPA/ULPA high-efficiency filters, and some including pre-filters for primary and medium-efficiency filters) needs to be replaced, it is necessary to combine three core dimensions: differential pressure monitoring, performance testing, and intuitive observation. At the same time, the usage environment and time period should also be taken into account. The following are the directly applicable judgment criteria and practical operation methods It is completely in line with the daily operation and maintenance scenarios of cleanrooms I. Core Judgment Basis: Differential Pressure Monitoring (the most direct and commonly used) The pressure difference change of the filter is a core indicator reflecting the degree of clogging. It needs to be monitored in real time through the pressure difference gauge (or an independently installed pressure difference transmitter) that comes with the equipment. The specific judgment criteria are as follows: 1. Pressure difference judgment of high-efficiency filters (HEPA/ULPA) Basic standard: When the measured pressure difference reaches “twice the initial pressure difference”, it must be replaced. For example, the initial pressure difference of the new HEPA filter is 100Pa. If the pressure difference rises to 200Pa or more after operation, it indicates that the

The supply air ceiling (also known as “laminar flow ceiling” or “purification ceiling”) is the core supply air terminal in clean rooms (such as operating rooms, pharmaceutical workshops, and microelectronics clean areas), and its performance directly determines the air cleanliness, uniformity of temperature and humidity, and airflow stability in the clean area. The following, in combination with industry standards (ISO 14644, GB 50591) and practical experience, elaborates in detail on daily maintenance norms and reasonable service life, taking into account both operability and professionalism: I. Daily Maintenance Specifications for Supply Air Ceilings (Implemented in Phases, with Key Points of Operation) (1) Daily maintenance (once before and once after each shift, 5-10 minutes) Core objective: Quickly identify appearance abnormalities and airflow stability issues to prevent immediate malfunctions from affecting production/surgery. Appearance and Cleaning Use a lint-free cloth dipped in 75% medical alcohol or a dedicated cleanroom cleaner to wipe the supply air panel (microplate/equal-flow membrane), the frame, and the surrounding areas to remove floating dust and stains (do not use cleaning tools/reagents containing fibers or corrosive substances to avoid particle contamination). Check whether the panel is deformed or loose, and whether the sealing rubber strip has fallen off (if the seal

I. Classification by Cleanliness Level (Core Standard for Medical Scenarios) Hospital supply air ceilings are classified into four cleanliness levels, each aligned with ISO 14644-1 standards, reflecting the required air quality for specific core hospital areas. Class I (Class 100 / ISO Class 4) – the highest cleanliness grade Core indicators: The number of particles ≥0.5μm in each cubic meter of air is ≤ 3,520, and the number of particles ≥5μm is ≤29. The microbial cleanliness is ≤ 0.2 CFU per dish. ​ Technical configuration: A vertical laminar flow organization is adopted, with wind speeds controlled between 0.45 and 0.55 m/s. It is equipped with HEPA high-efficiency filters (with a filtration efficiency of ≥99.97% for 0.3 μm particles), and ULPA ultra-high-efficiency filters (with a filtration efficiency of ≥99.999% for 0.12 μm particles) are used in some high-end scenarios. ​ Applicable scenarios: extremely high-risk surgeries such as organ transplantation, cardiac surgery, and neurosurgery, as well as core areas for sterile preparation production. The air supply surface should cover an area of ≥2.4m×1.8m on the operating table to prevent vortex contamination. ​ Class II uses vertical or horizontal laminar flow (0.25–0.3 m/s), with high-efficiency filters (≥99.9%), and may include a three-stage filtration

The core value of regular maintenance of negative pressure weighing rooms: multi-dimensional guarantees from compliance and safety to efficiency optimization As a key piece of equipment in high-cleanliness scenarios in industries such as pharmaceuticals, biology, and chemicals, the operation status of the negative pressure weighing chamber is directly related to production compliance, operational safety, and material handling accuracy. Scientific and standardized regular maintenance is not merely “equipment upkeep”, but a systematic management behavior covering compliance risk prevention and control, cost control, and efficiency improvement. The specific core benefits are as follows: 1. Ensure compliance and meet industry standards and auditing requirements 1. Comply with mandatory standards such as GMP/ISO The pharmaceutical, food, and other industries have clear and mandatory requirements for the operating parameters of clean equipment (such as cleanliness, negative pressure value, and filter integrity) (such as GMP, ISO 14644 series standards). Regular maintenance can ensure that the equipment continuously meets key indicators such as the cleanliness of the working area reaching ISO level 8 or above, the leakage rate of the HEPA filter being ≤0.01%, and the negative pressure being stable at -10Pa to -30Pa, avoiding serious consequences such as substandard production batches and product recalls due to

Daily Maintenance of Negative Pressure Weighing Rooms: Essential Steps for Clean Performance and Safety As a core cleaning equipment in the pharmaceutical, biological, chemical, and other industries, the operational stability of the negative pressure weighing chamber is directly related to the accuracy of material weighing, the health of operators, and the compliance of the production environment. Scientific and standardized daily maintenance can not only extend the service life of equipment, but also avoid production risks caused by problems such as substandard cleanliness and negative pressure failure. The following provides professional maintenance solutions for industry practitioners from three aspects: core maintenance dimensions, cycle norms, and key precautions. 1. Daily Maintenance Tasks: 1.1 Inspect equipment appearance and environment Clean the exterior and surrounding areas of the equipment to ensure there is no dust accumulation and no debris blocking the air inlet/outlet. Reserve at least 30cm of maintenance space around the equipment. Check whether the sealing rubber strip on the equipment door is intact, without deformation, cracking, or signs of aging. After closing, the sealing performance should meet the standard (a paper towel test can be conducted: place a paper towel between the door gaps, and there should be no sliding or falling).

Standard Procedure and Operating Specifications for HEPA/ULPA Filter Replacement HEPA/ULPA filters, as the core purification components of laminar flow hoods, their replacement quality directly affects the cleaning effect and the stability of equipment operation. They must strictly follow the full-process norms of “preparation – disassembly – installation – verification”, especially suitable for industries with strict cleanliness requirements, such as pharmaceuticals and electronics. The specific operation steps and precautions are as follows: I. Preparations Before Replacement (1) Confirmation of preconditions Replacement timing judgment: When the pressure difference of the filter screen reaches twice the initial pressure difference (generally, the initial pressure difference of HEPA filters is about 200-300Pa, and that of ULPA is about 300-400Pa), or when the cleanliness test does not meet the standards (such as excessive particle count in A-level areas), or when the filter screen is damaged or has an odor, it needs to be replaced immediately. The recommended regular replacement cycle is 1 to 2 years (specifically, depending on the usage environment and the equipment manual). Compliance and safety preparations: Replacement operations should be carried out during production breaks and reported to the production and quality departments in advance. Before entering the clean area, operators must wear

HEPA/ULPA filter replacement criteria and practical operation methods The replacement of HEPA/ULPA filters should be based on a comprehensive judgment of scientific testing data and actual operating conditions to avoid cost waste caused by premature replacement or failure of cleanliness due to delayed replacement. The following are the core judgment dimensions, practical operation methods, and precautions, which are applicable to clean scenarios such as pharmaceuticals, electronics, and laboratories: I. Core Judgment Dimension (Priority Ranking) (1) Common determination of pressure differences (the most direct basis Judgment criterion: When the pressure difference before and after the filter screen reaches 1.8 to 2.0 times the initial pressure difference, it needs to be replaced immediately. If the pressure difference suddenly drops (more than 50% lower than the initial value), it may be that the filter screen is damaged or the installation seal has failed. An emergency inspection and replacement are also required. Reference range: The initial pressure difference of HEPA filters is usually 200-300Pa (@rated air volume), and that of ULPA filters is 300-400Pa. For specific details, please refer to the equipment manual or the factory inspection report of the filter. Practical operation method Record the data of the differential pressure gauge every day

Core precautions for the installation and maintenance of laminar flow hoods The installation standardization of laminar flow hoods directly determines their cleaning effect and operational stability, while the scientific maintenance affects the service life and compliance of the equipment. It is necessary to strictly follow industry standards and equipment technical requirements. The specific precautions are as follows: I. Installation Precautions (1) Preparations before installation Environmental and site verification: Confirm that the installation area (such as a clean workshop in a pharmaceutical factory or a laboratory) has reached the preset cleanliness level (typically 10,000/100,000 grades), with a flat floor, no dust pollution, and well-sealed walls/ceilings to prevent external contaminants from seeping in. Reserve sufficient installation space to ensure that the distance between the laminar flow hood’s air outlet and the operating table surface meets the requirements (generally 300-500mm, specifically as per the equipment manual), and at the same time, reserve a maintenance passage (≥600mm) for subsequent maintenance. Equipment and accessories inspection: After opening the box, check whether the main body of the laminar flow hood, HEPA/ULPA filters, fans, control systems, sealing strips, and other accessories are complete, and whether there are any dents or deformations on the appearance. Check whether the

Class A laminar flow hoods are fundamental to pharmaceutical factories, serving as essential equipment for drug quality control and GMP compliance. Their core value lies in safeguarding product safety, supporting regulatory adherence, and enhancing operational competitiveness throughout pharmaceutical production. As critical purification systems, Class A laminar flow hoods underpin pharmaceutical quality by minimizing contamination, fulfilling GMP requirements, and protecting both the product and enterprise interests through reliable application in every production phase. First, strengthen the defense line for the quality and safety of drugs. In the production of pharmaceuticals, contaminants such as microorganisms and dust particles are the primary sources of risk that lead to product nonconformity. The A-class laminar flow hood, through A high-efficiency filtration system (HEPA/ULPA filter, filtration efficiency ≥99.999%@0.3μm), forms A vertical or horizontal unidirectional clean airflow, establishing a local A-class clean environment in key operation areas (such as aseptic preparation, filling, powder injection, sub-packaging, biological product sampling, etc.), and forcibly discharges contaminants within the area, avoiding cross-contamination of drugs. Especially for sterile drugs, highly active drugs and other categories with extremely high cleanliness requirements, A-level laminar flow hoods can control the particle concentration at the operation point within the strict range stipulated by GMP (the number

Daily Maintenance Guide for Laminar Flow Transfer Windows: Ensuring a Clean Environment and Stable Operation of Equipment Laminar flow transfer Windows, as the core “isolation transfer equipment” between cleanrooms and non-clean areas as well as regions of different cleanliness levels, their sealing performance, filtration efficiency and air flow organization directly affect the overall cleanliness of the cleanroom. Proper daily maintenance not only extends the service life of equipment but also avoids the risk of cross-contamination. It is suitable for scenarios with strict cleanliness requirements such as pharmaceutical, electronic, food, and biological laboratories. The following are detailed key points for daily maintenance: I. Daily Inspection: Basic status Confirmation (Every 10 minutes, at least once per shift) Appearance and seal inspection Check whether the transfer window box and door body are deformed, scratched or damaged, and whether the glass window is clean without stains or cracks to ensure a clear view. Verify the double-door interlock function: After closing one side door, try to open the other side door to confirm that they cannot be opened simultaneously (when the interlock fails, it should be immediately deactivated to avoid pressure difference imbalance in the clean area). Check the door sealing strip: Touch the sealing

I. Daily Basic Maintenance (Daily Mandatory) 1. Cleaning and disinfection standards Cleaning scope: Interior of the cavity (countertop, four walls, corners), contact surfaces of the door body, door handles, gaps of the sealing strips, and external surfaces can be wiped as needed. ​ Cleaning process First, use a lint-free cloth dipped in 75% medical alcohol to wipe and remove microorganisms and stains (high-risk scenarios such as biological laboratories need to be cleaned every shift). ​ Use a soft-bristled brush and neutral detergent to scrub the dust in the gaps of the sealing strip, then dry it with a dry cloth to prevent moisture and aging. ​ Dust in the interlock sensing area should be blown off with compressed air at a pressure of 0.3 to 0.5MPa to prevent signal obstruction. ​ Precautions: Do not rinse with water, do not use chlorine-containing disinfectants (corrosive to metals), and do not use hard objects such as steel wool balls (to avoid scratches on stainless steel). ​ 2. Function check before startup Power supply status: Confirm that the power supply is stable and the voltage meets the equipment requirements (to avoid F06 failure); ​ Door interlock test: Verify that both doors cannot be opened