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The core application of pleated high-efficiency filters in cleanrooms
As the core terminal equipment of the air purification system in clean workshops, the high-efficiency filter with separators plays an irreplaceable role in controlling the air quality. It ensures the stability of production processes and product quality by offering highly efficient particulate interception. Its main applications focus on cleanroom construction, meeting process requirements, and preventing pollution risks, as follows: I. Core Function Positioning: The “Last Line of Defense” for Clean EnvironmentsThe air purification system in a cleanroom usually uses three filtration stages: “coarse filtration → medium filtration → high efficiency filtration”. The high-efficiency filter with separators is at the last stage. It intercepts the remaining fine particles after previous filtration, including dust, pollen, bacteria, and viruses. This ensures that the air entering the room meets preset cleanliness standards. Its filtration rate for particles 0.3μm and above is over 99.97% (in line with HEPA standards). Some ultra-high-efficiency models (ULPA) exceed 99.999% filtration for 0.12μm particles. It is essential for achieving different clean grades such as Class 100, Class 1,000, and Class 10,000.
Ii. Core Applications by Scenario
The electronics manufacturing industry demands extremely high environmental cleanliness. Tiny particles can adhere to products like chips, semiconductor devices, and circuit boards. These particles may cause short circuits, signal distortion, or reduce product yield.
Application scenarios: Chip manufacturing workshops, semiconductor packaging and testing workshops, liquid crystal panel (LCD/OLED) production workshops, precision processing areas for electronic components, etc.
Core function: Intercept suspended particles in the production environment to prevent them from contaminating key materials and equipment such as photoresist, wafers, and precision electronic components. At the same time, it is combined with temperature and humidity control to provide a stable and clean environment for electronic processes, ensuring the smooth progress of high-precision procedures such as chip lithography and packaging.
(2) Clean workshops for biomedicine and medical devices
The production process in the biomedical field is directly related to the safety and efficacy of drugs. The cleanliness of medical devices (especially implantable and sterile ones) directly affects the risk of clinical use. Therefore, the prevention and control of microbial contamination is a core demand.
Application scenarios: Pharmaceutical preparation workshops (such as injection and sterile powder injection production areas), biological fermentation workshops, vaccine production workshops, sterile assembly workshops for medical devices, laboratories (biosafety laboratories, microbiological testing laboratories), etc.
Core function: On the one hand, it filters out bacteria, fungi and other microorganisms in the air to prevent them from entering the production process and contaminating drugs or medical devices; On the other hand, it prevents the spread of dust (such as powder) generated during the production process, while ensuring the respiratory health of the operators, meeting the strict requirements of GMP (Good Manufacturing Practice for Pharmaceutical Products).
(3) Clean workshops for aseptic production of food and beverages
For high-value-added and aseptic food and beverage products (such as aseptic filled beverages, health foods, infant formula foods, etc.), microbial contamination in the production environment is a key factor affecting the shelf life and safety of the products.
Application scenarios: Aseptic filling workshops, raw material processing areas for health food, clean production areas for infant food, food additive refining workshops, etc.
Core function: Filter bacteria, mold and dust particles in the air to prevent them from contaminating food raw materials, semi-finished products and finished products, reduce the risk of product deterioration and spoilage, and at the same time meet the QS (Quality and Safety) and HACCP (Hazard Analysis and Critical Control Point) system requirements for food production.
(4) Clean workshops for precision machinery and aerospace
In fields such as precision mechanical processing and aerospace component manufacturing, there are strict requirements for the dimensional accuracy and surface quality of products. The adhesion of tiny particles may lead to processing errors, surface scratches, and even affect the service life and performance of components.
Application scenarios: Precision bearing processing workshops, aero engine blade manufacturing areas, optical instrument (such as lens) production workshops, micro-electromechanical systems (MEMS) processing areas, etc.
Core function: Control the dust particles in the processing environment to prevent them from causing wear and tear on precision machine tools and measuring instruments. At the same time, prevent the particles from adhering to the surface of the workpiece and affecting the processing accuracy and product qualification rate, ensuring the production quality of high-precision products.(V) Other special clean scenarios
Laboratory and research clean areas: Such as nanomaterials laboratories and precision instrument analysis laboratories in universities and research institutions, it is necessary to maintain a high cleanliness environment through high-efficiency filters with separators to avoid the impact of external contamination on the accuracy of experimental data and research samples.
Hospital clean operating rooms and icus: Although some hospital scenarios prefer non-partitioned high-efficiency filters, in areas with high requirements for air volume and pressure resistance (such as the fresh air system in large operating rooms), partitioned high-efficiency filters are still in use. Their core function is to filter bacteria and viruses in the air and reduce the risk of postoperative infection.
Iii. Key Adaptation Points in the Application
Clean grade matching: Select the corresponding efficiency of the pleated high-efficiency filter based on the clean grade requirements of the factory building. For example, ULPA ultra-high-efficiency filters are usually chosen for Class 100 clean areas, while HEPA high-efficiency filters can be selected for Class 10,000 to 100,000 clean areas.
Air volume and resistance control: Select a filter of the appropriate size based on the size of the factory space and the ventilation volume requirements. At the same time, pay attention to the changes in its initial and final resistance to avoid affecting the system air volume due to excessive resistance and ensure stable filtration efficiency.
Installation and sealing assurance: Special sealant, gasket or liquid tank sealing technology is adopted to prevent air leakage through the gap between the filter and the installation frame. This is a key link to ensure that the clean environment meets the standards; otherwise, it may lead to the “failure” of cleanliness.
Temperature resistance and corrosion resistance compatibility: In some special process environments (such as high-temperature drying areas and chemical clean areas containing corrosive gases), it is necessary to select high-efficiency filters with separators that have temperature resistance and corrosion resistance (such as using special filter materials and frame materials) to avoid equipment damage that may affect the filtration effect.

Iv. Summary of Application Value
The high-efficiency filter with separators precisely intercepts tiny particles and microorganisms, establishing a stable and controllable core environmental foundation for clean workshops. Its application is directly related to the feasibility of the production process, the stability and compliance of product quality. In industries with strict environmental requirements such as electronics, biomedicine, and precision manufacturing, it is not only an essential device to meet industry standards and regulations, but also a key support for reducing production risks, improving product yield, and enhancing the core competitiveness of enterprises. As industrial manufacturing moves towards high precision and high cleanliness, the application scenarios of pleated high-efficiency filters will further expand, and at the same time, the requirements for their filtration efficiency, stability and adaptability will continue to increase.

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