I. Core Service Life of Negative Pressure Weighing Chamber (Industry General Standard) The conventional design service life is 8 to 12 years. The design life of core components (fans, filters, control systems) is 5 to 8 years. They need to be replaced regularly to maintain performance. If the maintenance is in place and the working conditions are good, the entire equipment can be extended for 10 to 15 years (only for compliant operation and maintenance scenarios). Ii. Key Influencing Factors (Ranked by Influence Weight) Core component wear and tear (weight 40%) Fan system: The wear of the motor bearings and impellers of the centrifugal fan/fan filter unit (FFU) directly affects the stability of negative pressure (under normal operating conditions, they need to be replaced every 5 to 8 years; frequent starts and stops or high-load operation will shorten the period to 3 to 5 years). Filtration system Primary filter (G4) : Replace every 6 to 12 months. If not replaced in time, it will cause overload of medium and high-efficiency filters, accelerating the clogging of high-efficiency filters (HEPA/ULPA) (the normal service life of high-efficiency filters is 1 to 3 years, and overload use will shorten it to 6 to 18

The negative pressure weighing chamber is a core specialized equipment in the raw material weighing and batching processes of pharmaceutical factories. Its functions revolve around three core demands: personnel safety, material purity, and environmental cleanliness. It is a key facility to ensure the compliance of drug production and product quality. Its specific functions are as follows: When the negative pressure weighing chamber is in operation, it maintains a negative pressure relative to the outside inside, and the airflow will flow unidirectionally from the outside to the inside to ensure the safety of the operators. When operators weigh and repackage highly active, toxic and allergenic active pharmaceutical ingredients, this air flow organization can effectively prevent harmful substances such as dust and aerosols from leaking into the production workshop, avoid inhalation or skin contact by operators, and reduce occupational health risks. The negative pressure weighing chamber is equipped with a high-efficiency filtration system (HEPA/ULPA) to ensure the purity of materials and the quality of drugs. The air entering the chamber is strictly filtered to remove particles, microorganisms and other pollutants in the air. On the one hand, it prevents external impurities from contaminating the active pharmaceutical ingredients in the weighing process and

High-efficiency exhaust devices refer to exhaust equipment with high ventilation efficiency, low energy consumption, and the ability to precisely control the direction and volume of air flow. Their core function is to quickly expel stale air, harmful gases, dust, and residual heat within a local or overall space, ensuring the safety and comfort of the air environment. Its application fields cover multiple sectors such as industrial production, medical and health care, commercial buildings, civil residences, and special scenarios. The specific classification and application scenarios are as follows: The field of industrial production This is the core application scenario of the high-efficiency exhaust device, mainly used to solve the problem of pollutant emissions generated in industrial processes, ensuring production safety and personnel health. Heavy industry and manufacturing: In metallurgical, chemical, and mechanical processing workshops, it is used to discharge harmful media such as welding fumes, metal dust, chemical waste gas, and volatile paint (VOCs). In casting and forging workshops, high-temperature waste heat and dust can be quickly discharged, reducing the workshop temperature and improving the working environment. In the electronic semiconductor industry: In clean workshops for chip manufacturing and circuit board production, a fresh air system is used in conjunction to

The core of the daily maintenance of high-efficiency exhaust devices is to ensure smooth airflow, effective filtration, and low-consumption operation of the equipment, while avoiding problems such as reduced exhaust efficiency, increased noise, and safety hazards caused by dust accumulation and component aging. The following is elaborated in the order of “core maintenance modules + cycles + key operation points”, taking into account both universality and industry adaptability: I. Basic Maintenance (Daily/Weekly, Operable by All staff) Operation status inspection (Daily) Check the operating sound of the fan: no abnormal sounds or vibrations, stable fan speed, and no jamming. Confirm the exhaust effect: By sensing the wind speed at the air outlet and the speed at which indoor odors/smoke are expelled, determine whether the exhaust is normal. Check the instrument data: If air volume, air pressure and temperature and humidity meters are equipped, record the data to ensure it is within the rated range (deviations need to be checked in time). External cleaning (weekly) Wipe the fan casing and control panel to remove surface dust and oil stains (in industrial scenarios, focus on cleaning accumulated oil stains). Clear debris from the air inlet and outlet: Remove obstructions from the air outlet

The supply air ceiling of the operating room is the core component of the air purification system in the clean operating room, directly affecting the cleanliness of the operating room and the safety of the surgical environment. Its daily maintenance should follow the principles of precision, standardization and regularity. The specific maintenance contents and procedures are as follows: I. Daily Inspection (Daily/Before and After Each Surgery) Visual inspection Check whether the ceiling panel for the supply air is flat, free from deformation and damage, and whether the sealing strips at the connection points are intact to prevent air leakage and affect the air flow organization. Check the cleanliness of the panel surface and promptly wipe off dust and stains with medical non-woven fabric dipped in neutral detergent to prevent accumulated dust from falling and contaminating the surgical area. Operation status check After turning on the purification system, observe whether the air velocity at the air outlet of the supply ceiling is uniform and there is no obvious abnormal noise (such as abnormal noise from the fan or panel vibration noise). Check the reading of the differential pressure gauge to ensure that the pressure difference between the operating room and the

The replacement cycle of the filters on the supply air ceiling of the operating room should be comprehensively determined based on the type of filter, the usage frequency of the operating room, the environmental dust load and the pressure difference monitoring data. The specific standards are as follows: Primary filter The regular replacement cycle is 1 to 3 months. If the average daily number of surgeries in the operating room is high, the amount of dust in the surrounding environment is large, or the reading of the differential pressure gauge reaches twice the initial differential pressure, it needs to be replaced immediately. After each operation, large particles of dust on the surface can be cleaned with a vacuum cleaner to extend the service life. Medium-efficiency filter The regular replacement cycle is 3 to 6 months. As a “pre-protection” for high-efficiency filters, it needs to be replaced in advance if there is a significant decrease in air volume, severe dust accumulation at the air outlet, or excessive pressure difference. High-efficiency filter The regular replacement cycle is 1 to 2 years. This is the core component of air purification in clean operating rooms, and the pressure difference monitoring data serves as the

Laminar flow sampling carts (also known as clean sampling carts) are mobile local clean environment equipment. Their core is to generate unidirectional clean air flow through a high-efficiency filtration system, creating a sterile and dust-free clean space in the sampling operation area. This prevents samples from being contaminated by environmental microorganisms and particles, while also protecting the safety of operators and the environment. Its application fields are highly focused on scenarios with extremely high requirements for sample purity, experimental accuracy, and production compliance. The core application fields and detailed scenarios are as follows: I. Pharmaceutical and Biopharmaceutical Industry (Core Application Areas) As a key piece of equipment for GMP compliance requirements in the pharmaceutical industry, laminar flow sampling vehicles are an “essential tool” in the production and inspection processes of drugs, mainly used to prevent deviations in inspection results or batch nonconformity of products caused by sample contamination. Pharmaceutical production process: Sampling of raw materials, intermediates and finished products (such as raw material powder, oral liquid preparations, tablets/capsules, sterile injections, etc.) to ensure that the sampling process complies with GMP (Good Manufacturing Practice) requirements and prevent environmental impurities from mixing into the samples. Biopharmaceutical process: Sampling of biological reagents, vaccines,

The core working logic of air purification and disinfection machines is “first purify particulate matter and harmful gases, and then kill microorganisms and bacteria”. Different devices will combine multiple technologies to achieve functions. The mainstream working principles can be divided into two major categories: purification technology and disinfection technology, as follows: I. Core Purification Technology (Removal of Particulate Matter and Harmful Gases) This type of technology mainly addresses common air pollution problems such as dust, hair, formaldehyde and odors. High-efficiency filtration technology (HEPA filter filtration) is the core technology of air purification, with the mainstream being H13/H14 grade HEPA filters. Its filter screen is made of superfine glass fibers interwoven, with pore diameters as low as 0.3 microns. Through interception, inertial collision, diffusion adsorption and other effects, it can capture fine particles such as PM2.5, pollen, dust mite excrement and pet dander in the air, and the filtration efficiency can reach over 99.97%. Filters are usually of composite structure, from the outside to the inside, they are coarse filters (for intercepting hair and large dust particles), HEPA filters (for intercepting fine particles), and activated carbon filters (for adsorbing harmful gases). Activated carbon adsorption technology: Activated carbon has a large number

The air purification and disinfection machine is a device that integrates air purification and sterilization and disinfection functions. With its comprehensive treatment capabilities for particulate matter, harmful gases, and microorganisms, it is widely used in multiple fields such as medical and health care, public buildings, industrial production, and family life. The specific classification and application scenarios are as follows 1. Medical and health care field This is one of the core application scenarios of air purification and disinfection machines, with extremely high requirements for the sterilization efficiency and cleanliness level of the equipment. Hospital departments: operating rooms, icus, neonatal wards, fever clinics, infectious disease wards, etc., can effectively remove bacteria, viruses (such as influenza virus, novel coronavirus), and fungal spores in the air, reducing the risk of cross-infection. General wards and outpatient clinics are used to improve the medical environment and reduce the infection probability for both patients and medical staff. Affiliated areas of medical institutions: pharmacies, laboratories, sterile wards, and temporary storage rooms for medical waste, to prevent the spread of bacteria and contamination of drugs and samples. Other medical scenarios: community clinics, dental clinics, and vaccination sites provide clean and safe treatment Spaces for both medical staff and

Laminar flow sampling vehicles are specialized equipment that provide a local 100-level clean environment. Through high-efficiency filtration and laminar flow air supply technology, they effectively reduce the risk of cross-contamination during sampling and the sampling process. They are widely used in fields with strict cleanliness requirements such as pharmaceuticals, biological products, food testing, and medical devices. I. Daily Application Scenarios and Operation Norms 1. Core application scenarios Pharmaceutical industry: Sampling of intermediate products for active pharmaceutical ingredients and preparations, and retention of finished products to ensure that the samples are not contaminated by environmental microorganisms and particulate matter, and meet the requirements of GMP (Good Manufacturing Practice for Drugs). Biological laboratory: Packaging and sampling of cell culture media and strain samples to prevent the invasion of miscellaneous bacteria and affect experimental results. Food testing: Sample collection and pretreatment of sterile food and health products to ensure the accuracy of testing data. Medical devices: Sampling and random inspection of sterile devices to prevent quality misjudgment caused by sample contamination. 2. Standard operating procedures Check before startup Make sure the equipment is placed stably, the power cord is firmly connected, and there is no damage or aging. Check that the outlet of

The construction cost of the negative pressure weighing room is in the medium to high range, while the maintenance cost is relatively controllable. The overall cost is directly related to the equipment specifications, technical configuration, and usage frequency. Specifically, it can be broken down into two parts: I. Construction Cost: The initial investment is relatively high, and there are three core influencing factors The hardware configuration of the equipment determines the basic cost The core components of the negative pressure weighing chamber include high-efficiency filtration systems (HEPA/ULPA), fan units, airflow control systems, differential pressure monitoring devices, stainless steel operation chambers, etc. The precision and quality of these components directly increase the cost. Conventional small and medium-sized weighing rooms (suitable for small-batch raw material weighing in pharmaceutical factories) : The construction cost is usually between tens of thousands and hundreds of thousands of yuan. Large-scale customized equipment (suitable for highly active materials and multi-station operation, and must comply with EU GMP/US FDA standards) : The cost can reach several hundred thousand yuan, with the main differences lying in additional configurations such as sealing performance, intelligent control systems, and explosion-proof design. The cost of installation and compliance certification cannot be ignored The

The negative pressure weighing chamber is a core specialized equipment for the weighing process of raw materials, excipients and intermediates in pharmaceutical factories. Its significance lies in four core dimensions: personnel safety protection, material purity guarantee, production environment control and compliance compliance. It is a key facility for pharmaceutical production to meet GMP (Good Manufacturing Practice) requirements. Ensure the occupational health and safety of operators In the process of pharmaceutical weighing, the active pharmaceutical ingredients and excipients are mostly in fine powder form, and some materials also have toxicity, corrosiveness, allergenicity or pharmacological activity. The negative pressure weighing chamber forms a stable unidirectional negative pressure airflow through an internal fan, making the indoor air pressure lower than that outdoors. The material dust will be quickly captured by the airflow and filtered through high-efficiency filters (HEPA/ULPA) to prevent the dust from escaping and spreading into the production workshop. This effectively prevents operators from inhaling harmful dust from the root and reduces the risk of occupational exposure. Prevent cross-contamination of materials and ensure the purity of drugs Pharmaceutical production has extremely high requirements for purity. If dust from different batches and types of materials cross-contaminates, it will directly affect the quality of