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What are the application scenarios of high-efficiency exhaust units in the pharmaceutical industry?
In the pharmaceutical industry, the high-efficiency exhaust unit mainly serves GMP compliance, personnel safety protection and environmental protection standards, covering key scenarios throughout the entire process from production, experimentation to auxiliary operations.
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Chemical Synthesis Workshop
Active pharmaceutical ingredient synthesis section: Discharge toxic and harmful gases (such as solvent vapor, hydrogen chloride, ammonia) produced by reaction vessels and distillation devices to prevent personnel poisoning and environmental leakage.
Intermediate production area: Treats volatile organic compounds (VOCs) from processes such as esterification and nitrification, and cooperates with waste gas treatment equipment to achieve standard emissions, meeting environmental protection requirements.
High-activity pharmaceutical ingredient (API) production area: Closed exhaust and high-efficiency filtration are adopted to prevent the spread of high-activity dust or aerosols, avoiding cross-contamination and occupational exposure of personnel.
Preparation production workshop
Solid dosage form crushing/screening/mixing section: Exhaust drug dust (such as dust from tablet and capsule raw materials) to prevent the risk of dust explosion and maintain the cleanliness of the workshop (meeting GMP grade D/above requirements).
Liquid formulation preparation/potting area: Discharge solvent volatile gases and acid and alkali waste gases to prevent equipment corrosion and affect product stability.
Aseptic preparation workshop (freeze-drying, filling area) : Discharge a small amount of microbial aerosols and disinfection gases (such as hydrogen peroxide vapor) generated during aseptic operations to ensure that the aseptic environment is not damaged.
Biopharmaceutical workshop
Fermentation section: Expel bioaerosols, metabolic waste gas and odors generated during the fermentation process to prevent the spread of harmful microorganisms.
Cell culture and purification area: Handle the volatile gases from the culture medium and the waste gas from acid-base elution solutions, while maintaining the pressure difference balance in the clean area to prevent cross-contamination.
Biosafety Laboratory (BSL-2/3 level) : For pathogenic microorganism aerosols generated from virus and bacterial culture, they are discharged in a targeted manner after high-efficiency filtration (HEPA) to prevent biosafety incidents.
Laboratory and quality inspection area
QC Laboratory (Physical and Chemical Testing Area) : Remove toxic solvent vapors (such as methanol, acetonitrile) and corrosive gases generated from reagent cabinets and titration experiments to protect the health of testing personnel.
Microbiology laboratory: Exhaust the exhaust gas from the incubator and the microbial aerosols generated during inoculation operations, in combination with the ultraviolet disinfection system, to reduce the risk of contamination.
Stability test chamber accessories: Expel the hot and humid gases and volatile substances of drugs inside the test chamber to maintain a stable test environment and ensure the accuracy of the test data.
Storage and material handling area
Hazardous chemicals warehouse (solvent and reagent storage) : Explosion-proof exhaust units are adopted to discharge volatile flammable gases (such as ethanol and acetone), reducing the risk of explosion.
Raw material crushing/feeding area: Dust from powdered raw materials is extracted to prevent dust accumulation and potential safety hazards, while also meeting the cleanliness requirements of GMP for material handling areas.
Waste temporary storage room: Expel harmful gases and odors produced by expired raw materials and waste intermediates to prevent pollution of the surrounding environment.
Auxiliary and environmental protection area
Cleaning and disinfection area (equipment cleaning and sterilization room) : Exhaust waste gas from acid and alkali cleaning solutions, steam, and residual gases of sterilizing agents (such as ethylene oxide) to prevent corrosion of equipment and harm to personnel health.
Wastewater treatment station: Extract and discharge malodorous gases (such as hydrogen sulfide and ammonia) produced during anaerobic/aerobic treatment processes to improve the working environment in the sewage treatment area.
Freeze dryer accessory: Discharge the solvent vapor sublimated during the freeze-drying process, and in combination with the condensation recovery system, increase the solvent recovery rate and reduce emissions.

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