A laminar flow hood is a purification device that provides a local dust-free and sterile working environment. Its core function is to control the dust, microorganisms and other contaminants in the working area at an extremely low level through an air filtration system (usually combined with high-efficiency filters), while forming a stable air flow barrier to prevent external contamination from entering. With this feature, it is widely applied in multiple fields with strict requirements for environmental cleanliness:
I. Life Sciences and biomedicine Field
Microbiological experiments: It is used for the isolation, culture and identification of bacteria, fungi, viruses and other microorganisms, to prevent experimental samples from being contaminated by miscellaneous bacteria in the environment, and at the same time protect operators from exposure to pathogenic microorganisms (some biosafety type laminar flow hoods can achieve bidirectional protection).
Cell and tissue culture: In animal cell culture, plant tissue culture, and stem cell research, it provides a sterile environment for cell growth to prevent cell contamination that could lead to experimental failure.
Molecular biology experiments: such as PCR amplification, gene cloning, nucleic acid extraction and other operations, it is necessary to avoid nucleic acid contamination or interference from exogenous DNA. A laminar flow hood can effectively reduce the residue of nucleic acid fragments in the environment.
Ii. Pharmaceutical and Pharmaceutical Industry
Preparation production: During the preparation and packaging of oral preparations, injections, ointments and other drugs, the super-clean bench can reduce the risk of drug contamination by microorganisms and dust, meeting the cleanliness requirements of GMP (Good Manufacturing Practice for Pharmaceutical Products).
The processing and extraction of traditional Chinese medicine: The preparation process of some high-purity traditional Chinese medicine extracts requires a sterile environment to avoid impurities affecting the efficacy or causing deterioration.
Pharmaceutical inspection: Experiments such as microbial limit tests and sterility tests on drugs must be conducted in a laminar flow hood to ensure the accuracy of the test results.
Iii. Medical and health care field
Clinical testing: such as the processing and analysis of samples like blood, urine, and cerebrospinal fluid, to prevent environmental pollutants from interfering with test results (such as misjudging bacterial culture results).
Operating room auxiliary: It serves as an auxiliary clean device in minor surgical operations (such as minimally invasive surgeries in ophthalmology and dermatology) or local trauma treatment, reducing the risk of wound infection.
Vaccine and biological product preparation: The production process of biological products such as vaccines, sera, and antibodies has extremely high requirements for sterility. The laminar flow hood is a key clean operation equipment.
Iv. Electronics and Precision Manufacturing Industry
Microelectronics manufacturing: In the production and assembly of semiconductor chips, integrated circuits, and circuit boards, tiny dust particles in the air may cause circuit short circuits or component failures. Laminar flow hoods can provide a clean environment of Class 100 (the number of particles ≥0.5μm per cubic foot of air ≤100) or even higher.
Precision instrument assembly: Such as the assembly of optical lenses, sensors, micro motors and other precision components, it is necessary to avoid dust adhesion that may affect product performance.
Electronic material processing: In the processes of photoresist coating and wafer cleaning, the laminar flow hood can prevent contaminants from affecting the purity and precision of the materials.
V. Food and Cosmetics Industry
Food microbiological testing: When isolating and identifying pathogenic bacteria in food (such as Escherichia coli and Salmonella), the operation should be carried out in a sterile environment to avoid contamination of the samples by environmental microorganisms.
High-end food production: such as aseptic filling of fruit juice, dairy products, health supplements, etc., the use of super-clean workbenches during raw material blending and packaging can extend the shelf life of the products.
Cosmetics research and development and production: For some high-purity cosmetics without preservatives (such as essence and facial masks), the raw material mixing and filling must be carried out in a sterile environment to prevent mold and bacterial contamination from causing product deterioration.
Vi. Agricultural and Environmental Monitoring Field
Plant tissue culture and breeding: In the tissue culture of crops and flowers, the super-clean bench can prevent miscellaneous bacteria from contaminating the culture medium and increase the survival rate of tissue culture seedlings. In the screening experiments of gene-edited crops, ensure that the operating environment is clean to avoid interference from exogenous genes.
Environmental microbial testing: When isolating and counting microorganisms in water, soil and air samples, a laminar flow hood is used to reduce the interference of environmental microorganisms on the test results.
Vii. Other Special Fields
Aerospace: In the assembly of precision electronic components or material testing of satellites and spacecraft, a super-clean environment is required to prevent dust from affecting the operation of the equipment in the space environment.
In the nuclear industry, during the handling of certain trace amounts of radioactive substances, the super-clean workbench can be used in conjunction with protective devices to reduce the risk of exposure for operators while ensuring a clean operating environment.
In conclusion, the core application scenarios of laminar flow hoods all revolve around the demand for “high local cleanliness to prevent contamination (samples, products, experimental results) or to protect operators”. The specific models (such as horizontal laminar flow, vertical laminar flow, and biosafety types) will be further subdivided and selected based on the cleanliness level and protection requirements of the scenarios.
I. Life Sciences and biomedicine Field
Microbiological experiments: It is used for the isolation, culture and identification of bacteria, fungi, viruses and other microorganisms, to prevent experimental samples from being contaminated by miscellaneous bacteria in the environment, and at the same time protect operators from exposure to pathogenic microorganisms (some biosafety type laminar flow hoods can achieve bidirectional protection).
Cell and tissue culture: In animal cell culture, plant tissue culture, and stem cell research, it provides a sterile environment for cell growth to prevent cell contamination that could lead to experimental failure.
Molecular biology experiments: such as PCR amplification, gene cloning, nucleic acid extraction and other operations, it is necessary to avoid nucleic acid contamination or interference from exogenous DNA. A laminar flow hood can effectively reduce the residue of nucleic acid fragments in the environment.
Ii. Pharmaceutical and Pharmaceutical Industry
Preparation production: During the preparation and packaging of oral preparations, injections, ointments and other drugs, the super-clean bench can reduce the risk of drug contamination by microorganisms and dust, meeting the cleanliness requirements of GMP (Good Manufacturing Practice for Pharmaceutical Products).
The processing and extraction of traditional Chinese medicine: The preparation process of some high-purity traditional Chinese medicine extracts requires a sterile environment to avoid impurities affecting the efficacy or causing deterioration.
Pharmaceutical inspection: Experiments such as microbial limit tests and sterility tests on drugs must be conducted in a laminar flow hood to ensure the accuracy of the test results.
Iii. Medical and health care field
Clinical testing: such as the processing and analysis of samples like blood, urine, and cerebrospinal fluid, to prevent environmental pollutants from interfering with test results (such as misjudging bacterial culture results).
Operating room auxiliary: It serves as an auxiliary clean device in minor surgical operations (such as minimally invasive surgeries in ophthalmology and dermatology) or local trauma treatment, reducing the risk of wound infection.
Vaccine and biological product preparation: The production process of biological products such as vaccines, sera, and antibodies has extremely high requirements for sterility. The laminar flow hood is a key clean operation equipment.
Iv. Electronics and Precision Manufacturing Industry
Microelectronics manufacturing: In the production and assembly of semiconductor chips, integrated circuits, and circuit boards, tiny dust particles in the air may cause circuit short circuits or component failures. Laminar flow hoods can provide a clean environment of Class 100 (the number of particles ≥0.5μm per cubic foot of air ≤100) or even higher.
Precision instrument assembly: Such as the assembly of optical lenses, sensors, micro motors and other precision components, it is necessary to avoid dust adhesion that may affect product performance.
Electronic material processing: In the processes of photoresist coating and wafer cleaning, the laminar flow hood can prevent contaminants from affecting the purity and precision of the materials.
V. Food and Cosmetics Industry
Food microbiological testing: When isolating and identifying pathogenic bacteria in food (such as Escherichia coli and Salmonella), the operation should be carried out in a sterile environment to avoid contamination of the samples by environmental microorganisms.
High-end food production: such as aseptic filling of fruit juice, dairy products, health supplements, etc., the use of super-clean workbenches during raw material blending and packaging can extend the shelf life of the products.
Cosmetics research and development and production: For some high-purity cosmetics without preservatives (such as essence and facial masks), the raw material mixing and filling must be carried out in a sterile environment to prevent mold and bacterial contamination from causing product deterioration.
Vi. Agricultural and Environmental Monitoring Field
Plant tissue culture and breeding: In the tissue culture of crops and flowers, the super-clean bench can prevent miscellaneous bacteria from contaminating the culture medium and increase the survival rate of tissue culture seedlings. In the screening experiments of gene-edited crops, ensure that the operating environment is clean to avoid interference from exogenous genes.
Environmental microbial testing: When isolating and counting microorganisms in water, soil and air samples, a laminar flow hood is used to reduce the interference of environmental microorganisms on the test results.
Vii. Other Special Fields
Aerospace: In the assembly of precision electronic components or material testing of satellites and spacecraft, a super-clean environment is required to prevent dust from affecting the operation of the equipment in the space environment.
In the nuclear industry, during the handling of certain trace amounts of radioactive substances, the super-clean workbench can be used in conjunction with protective devices to reduce the risk of exposure for operators while ensuring a clean operating environment.
In conclusion, the core application scenarios of laminar flow hoods all revolve around the demand for “high local cleanliness to prevent contamination (samples, products, experimental results) or to protect operators”. The specific models (such as horizontal laminar flow, vertical laminar flow, and biosafety types) will be further subdivided and selected based on the cleanliness level and protection requirements of the scenarios.
